منابع مشابه
SR-BI and fatty platelets.
Langerhans cell histiocytosis following T-ALL: clonally related neoplasms with persistent expression of constitutively active NOTCH1. Am J Hematol. 2008;83(2): 116-121. 7. Coury F, Annels N, Rivollier A, et al. Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. Nat Med. 2008;14(1):81-87. 8. Allen CE, McClain KL. Interleukin-17A is not expressed by CD2...
متن کاملC323 of SR-BI is required for SR-BI-mediated HDL binding and cholesteryl ester uptake.
Scavenger receptor BI (SR-BI) is an HDL receptor. It binds HDL and mediates the uptake of cholesteryl ester from HDL. Early studies have pointed out that the extracellular domain of SR-BI is critical for SR-BI-mediated cholesteryl ester uptake. However, the extracellular loop of SR-BI is large: it contains 403 amino acids. The HDL binding site and the modulation of SR-BI-mediated cholesteryl es...
متن کاملSR-BI/CD36 Chimeric Receptors Define Extracellular Subdomains of SR-BI Critical for Cholesterol Transport
High-density lipoproteins (HDLs) are athero-protective, primarily because of their ability to promote cholesterol flux from peripheral tissues to the liver by reverse cholesterol transport (RCT). The delivery of HDL-cholesteryl esters (CE) into cells is mediated by the HDL receptor, scavenger receptor class B type I (SR-BI), a promising target for enhancing whole body cholesterol disposal and p...
متن کاملMacrophage ABCA1 and SR-BI in Atherogenesis
Zhao et al report that two fatshifting factors work synergistically to keep macrophages healthy and atherosclerosis at bay. Despite their voracious appetite, macrophages are unable to fully digest the lipids they ingest. Instead, they rely on factors, such as ABCA1, to export excess cholesterol out of the cell. Lipid accumulation inside macrophages can result in their transformation into foam c...
متن کاملab - plane optical properties of Ni - doped Bi Sr CaCu
Ž . The ab-plane optical reflectance of single crystal of Bi Sr Ca Cu Ni O , for xs0.0215, has been measured 2 2 1yx x 2 8qd y1 Ž . from 80 to 40 000 cm 10 meV–5 eV and at temperatures between 20 and 300 K. Through Ni substitution, the optical conductivity shows a broad peak at about 400 cm, which grows in intensity and shifts to lower frequency as the temperature is reduced. We suggest that th...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2003
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000091271.12117.ab